Sunspot Dynamics Are Reflected in Human Physiology and Pathophysiology

Normal physiology and HIV pathophysiology of human T-cell dynamics.

Leptin in human physiology and pathophysiology.

Leptin, discovered through positional cloning 15 years ago, is an adipocyte-secreted hormone with pleiotropic effects in the physiology and pathophysiology of energy homeostasis, endocrinology, and metabolism. Studies in vitro and in animal models highlight the potential for leptin to regulate a number of physiological functions. Available evidence from human studies indicates that leptin has a...

The role of leptin in human physiology and pathophysiology.

This review focuses on current knowledge of leptin biology and the role of leptin in various physiological and pathophysiological states. Leptin is involved in the regulation of body weight. Serum leptin can probably be considered as one of the best biological markers reflecting total body fat in both animals and humans. Obesity in man is accompanied by increased circulating leptin concentratio...

HIGHLIGHTED TOPIC Pulmonary Physiology and Pathophysiology in Obesity Pulmonary physiology and pathophysiology in obesity

OBESITY is now a common occurrence in modern society. Barely one-third of Americans fall into the normal weight range, and 32% of the population has been classified as obese (9). The obesity epidemic is permeating into the childhood years, with 16.3% of children in the United States being above the 95th percentile for the body mass index (BMI), resulting in comorbidities such as the metabolic s...

The Physiology and Pathophysiology of the Hyperbaric and Diving Environments The physiology and pathophysiology of human breath-hold diving

Peter Lindholm and Claes EG Lundgren Department of Physiology and Pharmacology, Section for Anesthesiology and Intensive Care Medicine, Karolinska Insitutet, and Department of Radiology, Karolinska University Hospital, Stockholm, Sweden; and Center for Research and Education in Special Environments, and Department of Physiology and Biophysics, School of Medicine and Biomedical Sciences, Univers...